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Liping Deng, Ruotong Ren, Jun Wu, Keiichiro Suzuki, Juan Carlos Izpisua Belmote, Guang-Hui Liu. CRISPR/Cas9 and TALE: beyond cut and paste[J]. Protein&Cell, 2015, 6(3): 157-159. doi: 10.1007/s13238-015-0137-5
Citation: Liping Deng, Ruotong Ren, Jun Wu, Keiichiro Suzuki, Juan Carlos Izpisua Belmote, Guang-Hui Liu. CRISPR/Cas9 and TALE: beyond cut and paste[J]. Protein&Cell, 2015, 6(3): 157-159. doi: 10.1007/s13238-015-0137-5
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CRISPR/Cas9 and TALE: beyond cut and paste

    Abstract
  • Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal structures or genomic regions.
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