FTO stabilizes MIS12 and counteracts senescence

doi: 10.1007/s13238-022-00914-6

• Sheng Zhang^1,2,3 , 
• Zeming Wu^2,4,5 , 
• Yue Shi^6,7 , 
• Si Wang^8,9,10 , 
• Jie Ren^3,4,6,7,11 , 
• Zihui Yu^3,6,7 , 
• Daoyuan Huang⁸ , 
• Kaowen Yan^2,4,5 , 
• Yifang He^2,3,4,5 , 
• Xiaoqian Liu^4,5,12 , 
• Qianzhao Ji^2,3 , 
• Beibei Liu^6,7 , 
• Zunpeng Liu^3,12 , 
• Jing Qu^3,4,5,12 , 
• Guang-Hui Liu^{2,3,4,5,8,9 ,  ,}  , 
• Weimin Ci^{3,4,6,7 ,  ,}  , 
• Xiaoqun Wang^{1,3,4,13 ,  ,}  , 
• Weiqi Zhang^{3,4,6,7 ,  ,} 

• 1. State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Brain-Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China;

• 2. State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China;

• 3. University of Chinese Academy of Sciences, Beijing, 100049, China;

• 4. Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China;

• 5. Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China;

• 6. CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China;

• 7. China National Center for Bioinformation, Beijing, 100101, China;

• 8. Advanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China;

• 9. Aging Translational Medicine Center, International Center for Aging and Cancer, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China;

• 10. Chongqing Renji Hospital, University of Chinese Academy of Sciences, Chongqing, 400062, China;

• 11. Sino-Danish College, University of Chinese Academy of Sciences, Beijing, 101408, China;

• 12. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China;

• 13. Beijing Institute for Brain Disorders, Beijing, 100069, China