Volume 13 Issue 4
Mar.  2022
Turn off MathJax
Article Contents
Alejandro De Los Angeles, Jun Wu. New concepts for generating interspecies chimeras using human pluripotent stem cells[J]. Protein&Cell, 2022, 13(4): 234-238. doi: 10.1007/s13238-021-00880-5
Citation: Alejandro De Los Angeles, Jun Wu. New concepts for generating interspecies chimeras using human pluripotent stem cells[J]. Protein&Cell, 2022, 13(4): 234-238. doi: 10.1007/s13238-021-00880-5

New concepts for generating interspecies chimeras using human pluripotent stem cells

doi: 10.1007/s13238-021-00880-5
  • Publish Date: 2022-03-24
  • loading
  • [1]
    Aksoy I, Rognard C, Moulin A, Marcy G, Masaraud E, Wianny F, Cortay V, Bellemin-Menard A, Doerflinger N, Dirheimer M et al (2021) Apoptosis, G1 phase stall, and premature differentiation account for low chimeric competence of human and rhesus monkey naïve pluripotent stem cells. Stem Cell Rep 16:56-74
    [2]
    Das S, Koyano-Nakagawa N, Gafni O, Maeng G, Singh BN, Rasmussen T, Pan X, Choi K-D, Mickelson D, Gong W et al (2020) Generation of human endothelium in pigs deficient in ETV2. Nat Biotechnol 38:297-302
    [3]
    Hu Z, Li H, Jiang H, Ren Y, Yu X, Qiu J, Stablewski AB, Zhang B, Buck MJJ, Feng J (2020) Transient inhibition of mTOR in human pluripotent stem cells enable robust formation of mouse-human chimeric embryos. Sci Adv 6:eaaz0298
    [4]
    Hyun I (2019) Ethical standards for chimera research oversight. Methods Mol Biol 2005:165-171
    [5]
    Hyun I, Clayton EW, Cong Y, Fujita M, Goldman SA, Hill LR, Monserrat N, Nakauchi H, Pedersen RA, Rooke HM et al (2021) ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Rep 16:1409-1415
    [6]
    Kobayashi T, Yamaguchi T, Hamanaka S, Kato-Itoh M, Yamazaki Y, Ibata M, Sato H, Lee YS, Usui J, Knisely AS et al (2010) Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells. Cell 142:787-799
    [7]
    Maeng G, Das S, Greising SM, Gong W, Singh BN, Kren S, Mickelsen D, Skie E, Gafni O, Sorensen JR et al (2021) Humanized skeletal muscle in MYF5/MYOD/MYF6-null pig embryos. Nat Biomed Eng 5:805-814
    [8]
    Nishimura T, Suchy FP, Bhadury J, Igarashi KJ, Charlesworth CT, Nakauchi H (2021) Generation of functional organs using a cell-competitive niche in intra- and inter-species rodent chimeras. Cell Stem Cell 28:141-149
    [9]
    Posfai E, Schell JP, Janiszewski A, Rovic I, Murray A, Bradshaw B, Yamakawa T, Pardon T, El BakkaliTalon MI et al (2021) Evaluating totipotency using criteria of increasing stringency. Nat Cell Biol 23:49-60
    [10]
    Stirparo GG, Boroviak T, Guo G, Nichols J, Smith A, Bertone P (2018) Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast. Development 145:dev158501
    [11]
    Taei A, Kiani T, Taghizadeh Z, Moradi S, Samadian A, Mollamohammadi S, Sharii-Zarchi A, Guenther S, Akhlaghpour A, Abibeiglou BA et al (2020) Temporal activation of LRH-1 and RAR-G in human pluripotent stem cells induces a functional naïve-like state. EMBO Rep 21:e47533
    [12]
    Tan T, Wu J, Si C, Dai S, Zhang Y, Sun N, Zhang E, Shao H, Si W, Yang P et al (2021) Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo. Cell 184:2020-2032
    [13]
    Theunissen TW, Friedli M, He Y, Planet E, O'Neil RC, Markoulaki S, Pontis J, Wang H, Iouranova A, Imbeault M, Duc J et al (2016) Molecular criteria for defining the naïve human pluripotent state. Cell Stem Cell 19:502-515
    [14]
    Wu J, Platero-Luengo A, Sakurai M, Sugawara A, Gil MA, Yamauchi T, Suzuki K, Bogliotti YS, Cuello C, Valencia MM et al (2017) Interspecies chimerism with mammalian pluripotent stem cells. Cell 168:473-486
    [15]
    Yamaguchi T, Sato H, Kato-Itoh M, Goto T, Hara H, Sanbo M, Mizuno N, Kobayashi T, Yanagida A, Umino A et al (2017) Interspecies organogenesis generates autologous functional islets. Nature 542:191-196
    [16]
    Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, Xu Y, Dong J, Wang C, Lai W et al (2017) Derivation of pluripotent stem cells with in vivo embryonic and extraembryonic potency. Cell 169:243-257
    [17]
    Yu L, Wei Y, Sun HX, Mahdi AK, Pinzon Arteaga CA, Sakurai M, Schmitz DA, Zheng C, Ballard ED, Li J et al (2020) Derivation of intermediate pluripotent stem cells amenable to primordial germ cell specification. Cell Stem Cell 28:550-567
    [18]
    Zheng C, Hu Y, Sakurai M, Pinzon-Arteaga CA, Li J, Wei Y, Okamura D, Ravaux B, Barlow HR, Yu L et al (2021) Cell competition constitutes a barrier for interspecies chimerism. Nature 592:272-276
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)

    Article Metrics

    Article views (254) PDF downloads(23) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return