Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice

Jinliang Wang; Lei Shuai; Chong Wang; Renqiang Liu; Xijun He; Xianfeng Zhang; Ziruo Sun; Dan Shan; Jinying Ge; Xijun Wang; Ronghong Hua; Gongxun Zhong; Zhiyuan Wen; Zhigao Bu

doi:10.1007/s13238-020-00767-x

Volume 11 Issue 10

Sep. 2020

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Article Navigation > Protein&Cell > 2020 > 11(10): 776-782

Jinliang Wang, Lei Shuai, Chong Wang, Renqiang Liu, Xijun He, Xianfeng Zhang, Ziruo Sun, Dan Shan, Jinying Ge, Xijun Wang, Ronghong Hua, Gongxun Zhong, Zhiyuan Wen, Zhigao Bu. Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice[J]. Protein&Cell, 2020, 11(10): 776-782. doi: 10.1007/s13238-020-00767-x

Citation:

Jinliang Wang, Lei Shuai, Chong Wang, Renqiang Liu, Xijun He, Xianfeng Zhang, Ziruo Sun, Dan Shan, Jinying Ge, Xijun Wang, Ronghong Hua, Gongxun Zhong, Zhiyuan Wen, Zhigao Bu. Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice[J]. Protein&Cell, 2020, 11(10): 776-782. doi: 10.1007/s13238-020-00767-x

Citation:

Jinliang Wang, Lei Shuai, Chong Wang, Renqiang Liu, Xijun He, Xianfeng Zhang, Ziruo Sun, Dan Shan, Jinying Ge, Xijun Wang, Ronghong Hua, Gongxun Zhong, Zhiyuan Wen, Zhigao Bu. Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice[J]. Protein&Cell, 2020, 11(10): 776-782. doi: 10.1007/s13238-020-00767-x

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Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice

doi: 10.1007/s13238-020-00767-x

1 State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China;
2 National High Containment Laboratory for Animal Diseases Control and Prevention, Harbin 150069, China

Funds:

This work was supported by the National Key R&D Program of China (2020YFC0846500, 2018YFC1200601, 2020YFC0841100) and Applied Technology Research and Development Project of Heilongjiang Province, China (GA20C006).

Publish Date: 2020-09-27

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References(14)

References

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