Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids

doi: 10.1007/s13238-020-00718-6

• Bing Zhao^{1 ,  ,}  , 
• Chao Ni¹ , 
• Ran Gao² , 
• Yuyan Wang³ , 
• Li Yang¹ , 
• Jinsong Wei¹ , 
• Ting Lv⁴ , 
• Jianqing Liang¹ , 
• Qisheng Zhang⁵ , 
• Wei Xu³ , 
• Youhua Xie³ , 
• Xiaoyue Wang² , 
• Zhenghong Yuan³ , 
• Junbo Liang^{2 ,  ,}  , 
• Rong Zhang^{3 ,  ,}  , 
• Xinhua Lin^{1 ,  ,} 

• 1 State Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, China;

• 2 State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China;

• 3 Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China;

• 4 Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, China;

• 5 Sino Organoid Lifesciences Ltd., Shanghai 201900, China