Latest Articles

Correction to: Neuroendocrine characteristics of induced pluripotent stem cells from polycystic ovary syndrome women
Zheying Min, Yue Zhao, Jing Hang, Yun Ren, Tao Tan, Yong Fan, Yang Yu
 doi: 10.1007/s13238-019-00664-y
Qi Fang: Affective interweave with patients
Tanping Fu, Wenli Duan, Mingyan Chen, Shuyang Zhang
 doi: 10.1007/s13238-019-00667-9
Kuo-Hua Sun: The founder of physiologic psychology and child psychology in China
Yimeng Wang, Yanyan Qian
 doi: 10.1007/s13238-019-00666-w
Binding to m6A RNA promotes YTHDF2-mediated phase separation
Jiahua Wang, Liyong Wang, Jianbo Diao, Yujiang Geno Shi, Yang Shi, Honghui Ma, Hongjie Shen
 doi: 10.1007/s13238-019-00660-2
Professor Haowen Xu: The founder of exercise biochemistry in China
Wei Gong, Yijing Shen, Jiaqi Bao, Yike Ying, Han Zhou, Zhifeng Wu
 doi: 10.1007/s13238-019-00663-z
Chi-Nan Hu-Pioneer of Chinese neuroscience and cognitive science
Yunjin Wang, Yanyan Qian
 doi: 10.1007/s13238-019-00658-w
Shu-szi Sin: A Chinese pioneer biologist, ancient agronomist, and educator
Qun Xie, Yan-ping Cheng, Lei Fu
 doi: 10.1007/s13238-019-00657-x
A pioneer of modern Chinese Physiology: Dr. Robert Kho-Seng Lim
Fang Zhang
 doi: 10.1007/s13238-019-00655-z
Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b
Wei Li, Wenchen Shen, Bo Zhang, Kuan Tian, Yamu Li, Lili Mu, Zhiyuan Luo, Xiaoling Zhong, Xudong Wu, Ying Liu, Yan Zhou
 doi: 10.1007/s13238-019-0650-z
The mechanisms underlying spatial and temporal control of cortical neurogenesis of the brain are largely elusive. Long non-coding RNAs (lncRNAs) have emerged as essential cell fate regulators. Here we found LncKdm2b (also known as Kancr), a lncRNA divergently transcribed from a bidirectional promoter of Kdm2b, is transiently expressed during early differentiation of cortical projection neurons. Interestingly, Kdm2b's transcription is positively regulated in cis by LncKdm2b, which has intrinsic-activating function and facilitates a permissive chromatin environment at the Kdm2b's promoter by associating with hnRNPAB. Lineage tracing experiments and phenotypic analyses indicated LncKdm2b and Kdm2b are crucial in proper differentiation and migration of cortical projection neurons. These observations unveiled a lncRNA-dependent machinery in regulating cortical neuronal differentiation.
Professor Cuifen Huang: a great molecular geneticist and the founder of genetic engineering in China
Wei Gong, Leyi Cui, Yike Ying, Yijing Shen, Jiaqi Bao
 doi: 10.1007/s13238-019-0620-5
Richang Cao: pioneer advocate of dialectical materialism applied to psychological research
Baoyuan Zhang
 doi: 10.1007/s13238-019-0615-2
Correction to: Developing potent PROTACs tools for selective degradation of HDAC6 protein
Zixuan An, Wenxing Lv, Shang Su, Wei Wu, Yu Rao
 doi: 10.1007/s13238-019-0613-4
Professor Li-Pin. King: a famous physiologist in China
Wei Gong, Fangfang Wang, Yike Ying
 doi: 10.1007/s13238-018-0582-z
Zing-Yang Kuo and behavior epigenesis based on animal experiments
Yanyan Qian, Wei Chen, Benyu Guo
 doi: 10.1007/s13238-018-0516-9
Retraction Note to: DDB1 and Cul4 are necessary for gene silencing and heterochromatin formation at pericentromeric regions in Neurospora
Yingqiong Cao, Jicheng Wei, Silu Yang, Jinquan Sun, Hui Xu, Ying Wang, Yuanbiao Zhao, Qun He
 doi: 10.1007/s13238-014-0079-3
RETRACTED ARTICLE: DDB1 and Cul4 are necessary for gene silencing and heterochromatin formation at pericentromeric regions in Neurospora
Yingqiong Cao, Jicheng Wei, Silu Yang, Jinquan Sun, Hui Xu, Ying Wang, Yuanbiao Zhao, Qun He
 doi: 10.1007/s13238-014-0067-7
Just for Chinese people's stood up-Prof. Fangzhou Gu, father of “sugar pills”
Jun Wu, Dexiang Dong, Ying Li
 doi: 10.1007/s13238-019-00669-7
Correction to: Characterization of oogonia stem cells in mice by Fragilis
Xiaoyan Sheng, Chenglei Tian, Linlin Liu, Lingling Wang, Xiaoying Ye, Jie Li, Ming Zeng, Lin Liu
 doi: 10.1007/s13238-019-00675-9
Lifting the veil on the keratinocyte contribution to cutaneous nociception
Matthieu Talagas, Nicolas Lebonvallet, François Berthod, Laurent Misery
 doi: 10.1007/s13238-019-00683-9
Cutaneous nociception is essential to prevent individuals from sustaining injuries. According to the conventional point of view, the responses to noxious stimuli are thought to be exclusively initiated by sensory neurons, whose activity would be at most modulated by keratinocytes. However recent studies have demonstrated that epidermal keratinocytes can also act as primary nociceptive transducers as a supplement to sensory neurons. To enlighten our understanding of cutaneous nociception, this review highlights recent and relevant findings on the cellular and molecular elements that underlie the contribution of epidermal keratinocytes as nociceptive modulators and noxious sensors, both under healthy and pathological conditions.
Correction to: DNMT3A reads and connects histone H3K36me2 to DNA methylation
Wenqi Xu, Jiahui Li, Bowen Rong, Bin Zhao, Mei Wang, Ruofei Dai, Qilong Chen, Hang Liu, Zhongkai Gu, Shuxian Liu, Rui Guo, Hongjie Shen, Feizhen Wu, Fei Lan
 doi: 10.1007/s13238-019-00678-6
LHX6 is essential for the migration of human pluripotent stem cell-derived GABAergic interneurons
Fang Yuan, Kai-Heng Fang, Yuan Hong, Shi-Bo Xu, Min Xu, Yufeng Pan, Yan Liu
 doi: 10.1007/s13238-019-00686-6
Crystal structures of N-terminal WRKY transcription factors and DNA complexes
Yong-ping Xu, Hua Xu, Bo Wang, Xiao-Dong Su
 doi: 10.1007/s13238-019-00670-0
Phase separation of the C. elegans Polycomb protein SOP-2 is modulated by RNA and sumoylation
Wenyan Qu, Zheng Wang, Hong Zhang
 doi: 10.1007/s13238-019-00680-y
Atomic-resolution view of complete TCR-CD3 revealed
Jijie Chai
 doi: 10.1007/s13238-019-00677-7
Current issue
  • ISSN1674-800X
  • EISSN1674-8018
  • IF (2018) 7.575

Microbiota and Human Health

May 2018
Volume 9
Issue 5
pp: 395-510

Metabolism and Disease

May 2018
Volume 9
Issue 2
pp: 141-237

Therapeutic Antibodies

May 2018
Volume 9
Issue 1
pp: 1-139


Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang Beijing 100101, China

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