For Authors

General Information
Editorial Policies
Submission Requirements
           Cover letter
           Manuscript components
           Supplemental materials
           Compliance with ethics guidelines
           Data availability of structural studies
Language Assistance

General Information

Protein & Cell publishes novel research of special significance in biological and biomedical fields, focusing on protein and cell research. Our subject areas include, but are not limited to biochemistry, biophysics, cell biology, oncology, genetics, immunology, microbiology, molecular biology, neuroscience, stem cell, plant science, protein science, structural biology and translational medicine.

Submissions of the following types are invited:
a) Research articles: original experimental reports within the journal's scope.
b) Reviews, Mini-reviews: comprehensive, authoritative descriptions of any subject within the journal's scope. They may cover basic     science and clinical reviews.
c) Vantage points, Perspectives: advanced/preliminary/provocative observation/hypothesis on cutting edge subjects.
d) News and views, Highlights, Commentaries: up-to-date research highlights and commentaries covering research policies and funding trends in China as well as in other countries.
e) Recollection: historic stories about science and scientists.

Papers that have been reviewed, if the authors choose, may be submitted with previous reviews and decision letters. This allows for accelerated review.

When a manuscript is submitted, the Editors assume that no similar paper has been or will be submitted for publication elsewhere. Further, it is understood that all authors listed on a manuscript have agreed to its submission. Papers will be published online within two weeks after acceptance.

Editorial policies

All original articles are subject to strict peer review organized by the Editorial team, who will select two or more reviewers with relevant expertise. Should a split recommendation occur among reviewers, more reviewers may be selected upon Editor or the Board member's discussion. Final acceptance or rejection decision will be made by Editor-in-Chief of Protein & Cell. In general, the review process takes up to three weeks from the date of submission, and the Editors will make every effort to reach a decision on a manuscript within this timeline. If revisions are required for further consideration for publication, we generally allow three months for revisions and only one round of revisions will be considered.

Submission Requirements

Cover letter

A cover letter from the corresponding author must accompany the manuscript and should provide a brief description of what was known in the field, the conceptual breakthrough, the significant impact of the reported findings, and other important information that should be considered by Editorial team. The authors are encouraged to suggest appropriate reviewers and are permitted to make request for up to three reviewer exclusions. Cover letter should state that the submitted material is original research, has not been previously published, and has not been submitted elsewhere while under review by Protein & Cell. The cover letter is confidential and will not be sent to the reviewers.

Manuscript components

Manuscript should be arranged in the following order: (a) Title section (including Title, Running title, Keywords, Authors, Author Affiliations, and Correspondence). (b) Abstract. (c) Introduction. (d) Results. (e) Discussion. (f) Materials and Methods. (g) Footnotes, including Acknowledgements, Abbreviations and Compliance with ethics guidelines. (h) References. (i) Figure legends. (j) Tables. (k) Figures. (l) Supplementary materials.


NOTE: No specific formats are required for your texts or references, provided that they are readable and clear enough both in print and electronic versions.


Figures should be presented in the order they are mentioned in the text. Figures divided into parts should be labeled with an upper-case letter (Arial Font). Figures with several parts should also be in proportion, with consistently sized lettering so that the whole figure can be reduced by the same amount to the smallest size at which the essential details are visible. Images must be final size, preferably one column width (8.4 cm). Figures wider than one column should not be sized over 17 cm. The maximum height should not be higher than 20 cm. Numbers, letters, and symbols should be no smaller than 6 points (2 mm) and no larger than 12 points (6 mm) after reduction and must be consistent. Composite figures must be preassembled. The final text should be at least 2 mm in size and the graph lines should be at least 0.5 pt in weight.

Non-vector graphics should be preserved at high resolution: 300 dpi minimum at final size for greyscale or colour halftone images, and 600 dpi minimum for bitmap (b/w) artwork. Combinations of monochrome and greyscale/photographs should be at 600 dpi, and line arts should be 1,200 dpi.

For publication, we require PowerPoint, TIFF, AI or EPS files in PC format, preferably from PhotoShop or Illustrator software. For any figures submitted in photoshop or tiff format we require layered files to be sent whereby all text, arrows or additional attributes are placed on individual layers within the file. For line art/charts/graphs we prefer to work with Adobe Illustrator AI or EPS files.


NOTE: For peer-review, the submission of high-resolution PDF files will be appreciated. However, the original figure files will be requested upon acceptance. Figures must be submitted as separate files, not embedded in manuscript text.

If you have any questions about digital files, please contact

Supplementary materials

Supplementary materials that are directly related to the work are welcomed. However, unrelated data may be removed by editors. Depending on the nature of supplemental materials, they can be in plain text, MS Word, MS Excel, JPEG, TIFF, video We encourage authors to submit supplemental documents in PDF format if applicable.

Compliance with ethics guidelines

In order to comply with the ethical requirements, the following sentences should be included in a separate section of each article just before the reference list. The section should be called “COMPLIANCE WITH ETHICS GUIDELINES”.
Conflict of Interest:

When an author or the institution of the author has a relationship, financial or otherwise, with individuals or organizations that could influence the author’s work inappropriately, a conflict of interest may exist. Examples of potential conflicts of interest may include but are not limited to academic, personal, or political relationships; employment; consultancies or honoraria; and finical connections such as stock ownership and funding. Although an author may not feel that there are conflicts, disclosure of relationships and interests that could be viewed by others as conflicts of interest affords a more transparent and prudent process. General collective statements like “The authors declare that there is no Conflict of Interest” is NOT sufficient. The Conflict of Interest statements should list each author separately by name:

John Smith declares that he has no conflict of interest.

Paula Taylor has received research grants from Drug Company A.

Mike Schultz has received a speaker honorarium from Drug Company B and owns stock in Drug Company C.

If multiple authors declare no conflict, this can be done in one sentence:

John Smith, Paula Taylor, and Mike Schultz declare that they have no conflict of interest
For studies with human subjects include the following:

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000 (5). Informed consent was obtained from all patients for being included in the study.

If doubt exists whether the research was conducted in accordance with the Helsinki Declaration, the authors must explain the rationale for their approach, and demonstrate that the institutional review body explicitly approved the doubtful aspects of the study.
If any identifying information about patients is included in the article, the following sentence should also be included:

Additional informed consent was obtained from all patients for which identifying information is included in this article.
For studies with animals include the following sentence:

All institutional and national guidelines for the care and use of laboratory animals were followed.
For articles that do not contain studies with human or animal subjects performed by any of the authors:

While it is not absolutely necessary, we recommend to include the following sentence, just to make sure that readers are aware that there are no ethical issues with human or animal subjects:

This article does not contain any studies with human or animal subjects performed by the any of the authors.

Data availability of structural studies

For papers describing structures of biological macromolecules and small molecules, the atomic coordinates and the related experimental data must be deposited at a member site of the Worldwide Protein Data Bank ( RCSB PDB (, PDBe (, PDBj (, or BMRB ( The PDB ID should be included in the manuscript. Authors must agree to release the atomic coordinates and experimental data when the associated article is published.


Please submit your complete manuscript to Protein & Cell editorial office through online submission system or through email (


We do not charge any submission/publication fee.

Language Assistance

Authors who are not native English speakers may appreciate assistance with grammar, vocabulary, and style. This can improve the accuracy and facilitate the communication with other scientists and reviewers. Some companies provide revising, editing, and proofreading services for scientific and medical research documents are listed:

Please note that Protein & Cell does not use these services and will not guarantee the quality of their work.

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